Ipamorelin

What is it?

Ipamorelin is a small synthetic peptide that mimics ghrelin (the “hunger hormone”) to stimulate growth hormone release from the pituitary gland. It is notable for doing this without triggering unwanted side effects on other hormones.

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Key Benefits (from research)

– Selective growth hormone release – Ipamorelin stimulates GH without raising cortisol, prolactin, or ACTH – a cleaner profile than older compounds in its class.

– Supports bone mineral content – A 12-week animal study found increased bone mineral content in the femur, suggesting skeletal benefits from GH stimulation.

– Body composition research – Reviews link Ipamorelin to reduced fat and preserved lean
mass in research models of metabolic decline.

– Ageing and sarcopenia research – Consistently identified in gerontology literature as relevant to age-related GH decline and muscle loss.

– Amplifies GH pulse size – Research confirms it specifically increases the height of individual GH pulses, which has distinct effects on lean tissue beyond simply raising average GH levels.

– Cardioprotective signalling – Research into the broader compound class documents pro- survival heart cell effects through shared receptor pathways.

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Quick Q&A

What is Ipamorelin used for in research?
It is studied as a selective growth hormone stimulant, used to investigate GH pulsatility, body composition changes, and age-related GH decline.

Is it approved for people?
No – it is sold for laboratory research only.

Important Notice
Sold for laboratory research only. Not for human use. Must be 18+.

More information
Ipamorelin is a selective growth hormone secretagogue and ghrelin receptor agonist. As a pentapeptide, it stimulates GH release from the anterior pituitary with high selectivity, producing minimal cortisol or prolactin elevation compared to older GHRPs. It is among the most widely studied peptides for its clean GH release profile in preclinical research. For laboratory research use only.