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Also known as: Vasoactive Intestinal Peptide, VIP-28
What is it?
VIP is a 28-amino-acid peptide found throughout the nervous and immune systems. It is sometimes described as the body’s built-in anti-inflammatory signal. Research covers its roles in immunity, brain protection, gut health, and the body’s internal clock.
Key Benefits (from research)
– Calms autoimmune inflammation – Research shows VIP shifts immune responses away from aggressive inflammatory states and towards regulatory, tolerant ones.
– Protects dopamine nerve cells – Studies in Parkinson’s disease animal models show VIP protects the dopamine-producing nerve cells that are lost in that condition.
– Supports amyloid clearance in the brain – Research in Alzheimer’s mouse models documents VIP enhancing the brain’s own clean-up cells to remove amyloid protein deposits.
– Controls the body’s internal clock – VIP is a critical synchronising signal in the master circadian clock region of the brain; mice without VIP lose normal daily rhythms.
– Regulates gut immunity – VIP controls intestinal movement, secretion, and immune
tolerance in the gut lining — a primary area of its biological activity.
– Broad neurological research – VIP is studied in multiple sclerosis, autism, and neuropsychiatric models, where its signalling plays a role in limiting immune-related brain damage.
Quick Q&A
What is VIP used for in research?
It is studied for its roles in calming inflammation, protecting dopamine nerve cells, clearing amyloid, controlling circadian rhythms, and regulating gut immune function.
Is it approved for people?
No it is sold for laboratory research only.
Important Notice
Sold for laboratory research only. Not for human use. Must be 18+.
More Information
VIP (Vasoactive Intestinal Peptide) is a 28-amino acid neuropeptide member of the secretin/glucagon family. Acts on VPAC1 and VPAC2 receptors and has been studied for vasodilation, smooth muscle relaxation, bronchodilation, circadian rhythm regulation, and immunomodulation. Increasingly studied in the context of neuroimmunology. For laboratory research use only.
