NAD+

Also known as: Nicotinamide Adenine Dinucleotide, B-NAD, Coenzyme I

What is it?
NAD+ is one of the most important molecules in every living cell. It powers hundreds of chemical reactions and feeds the “longevity enzymes” (sirtuins) that regulate ageing, DNA repair, and energy production. NAD+ levels drop steadily throughout life.

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Key Benefits (from research)

– Powers the longevity enzyme system – Sirtuins – the enzymes most associated with longevity biology — can only function when NAD+ is present. Research shows restoring NAD+ activates these enzymes and mirrors some effects of caloric restriction.

– Supports DNA repair — NAD+ is the fuel for PARP enzymes, which repair broken DNA strands. Age-related increases in DNA damage accelerate NAD+ depletion.

– Supports energy production in cells — NAD+ is essential for the cellular machinery that converts food into usable energy, including the electron transport chain.

– Linked to reduced neurodegeneration – Falling NAD+ levels have been connected to Alzheimer’s and Parkinson’s research, with precursor supplementation studied as a protective approach.

– Age-related decline is well-documented – Research across multiple tissues confirms NAD+ falls with age and correlates with metabolic dysfunction and inflammation.

– Precursor supplementation in early human trials — NAD+ precursors (NMN and NR) are in early-phase clinical investigation and show promising safety and bioavailability data.

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Quick Q&A

What is NAD+ used for in research?
It is used as an analytical reference standard and to study ageing biology, DNA repair, mitochondrial function, and neuroprotection.

Is it approved for people?
NAD+ and its precursors are available as dietary supplements. The analytical reference standard sold here is for laboratory research and is not for consumption as a supplement.

Important Notice
Sold for laboratory research only. Not for human use. Must be 18+.

More information
NAD+ (Nicotinamide Adenine Dinucleotide) is a critical coenzyme found in every living cell, central to energy metabolism, DNA repair, and sirtuin activation. NAD+ levels decline with age, making it a key target in longevity and metabolic research. Supplied as a high-purity lyophilised powder for research use. For laboratory research use only.