KPV

What is it?
KPV is a tiny three-amino-acid peptide taken from the tail end of a natural anti-inflammatory hormone (alpha-MSH). Research shows it is one of the most potent inhibitors of NF-κB — a master switch that drives inflammation – using a mechanism that does not require a hormone
receptor.

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Key Benefits (from research)

– Reduces gut inflammation – Research in colitis animal models shows KPV reduces inflammatory cytokines and decreases the incidence of bowel inflammation.

– Accelerates mucosal healing — Studies with targeted nanoparticle delivery showed KPV accelerates recovery of wounded gut lining in ulcerative colitis models.

– Potent NF-κB suppressor – Research documents up to 80% reduction in this key inflammation switch across multiple tissue and cell models.

– Calms skin inflammation – Animal studies show KPV suppresses contact dermatitis reactions and reduces inflammatory markers in skin blood vessels.

– Supports chronic wound healing – Research documents KPV helps shift chronic wounds from a stuck inflammatory state into the repair phase.

– Has antimicrobial activity – Studies confirm KPV kills Staphylococcus aureus and Candida albicans directly, relevant to infected wound research.

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Quick Q&A

What is KPV used for in research?
It is studied for its potent anti-inflammatory effects in the gut, skin, and wounds, and for its direct antimicrobial activity.

Is it approved for people?
No it is sold for laboratory research only.

Important Notice
Sold for laboratory research only. Not for human use. Must be 18+.

More Information
KPV is the C-terminal tripeptide of alpha-Melanocyte Stimulating Hormone (alpha-MSH). It retains significant anti-inflammatory activity of the parent molecule by acting on melanocortin receptors and directly inhibiting NF-kB pathways. Studied in models of inflammatory bowel disease, skin inflammation, and wound healing. For laboratory research use only.